Vitacancer is a specialized formulation that combines the therapeutic properties of the cannabis plant in one product, utilizing broad-spectrum Cannabidiol (CBD) oil. 

​Anorexia and Inappetence: CBD has shown potential in influencing appetite by interacting with the body's endocannabinoid system, which plays a crucial role in regulating appetite, metabolism, and energy balance. CBD works indirectly, potentially affecting the release of hormones related to hunger, such as leptin and ghrelin.

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Anxiety and Stress Reduction: CBD helps alleviate anxiety and stress in cancer patients by interacting with the body's endocannabinoid system, which plays a key role in regulating mood, stress response, and emotional well-being. Research has shown that CBD acts on serotonin receptors, particularly the 5-HT1A receptor, which is responsible for regulating mood, anxiety, and stress. By enhancing serotonin signaling, CBD can produce anxiolytic (anxiety-reducing) effects similar to those of traditional antidepressants, offering relief from the emotional distress often experienced by cancer patients.

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Anti-inflammatory and analgesic properties: CBD's anti-inflammatory properties are primarily due to its ability to modulate the endocannabinoid system (ECS), which plays a crucial role in regulating immune responses and inflammation. By activating CB2 receptors, which are primarily located in immune cells, CBD helps reduce the production of pro-inflammatory cytokines and decreases the overall inflammatory response. This is particularly important for cancer patients, as chronic inflammation can exacerbate pain and lead to further complications in their condition.

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In addition to reducing inflammation, CBD offers significant pain relief by interacting with various pain pathways in the body. CBD influences TRPV1 receptors, which are involved in the sensation of pain and temperature regulation. By desensitizing these receptors, CBD can help mitigate pain signals. Furthermore, CBD enhances the body's natural endocannabinoids, such as anandamide, which are known to have pain-relieving properties. By preventing the breakdown of these endocannabinoids, CBD helps prolong their effects, offering longer-lasting pain relief.

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Cell apoptosis: CBD also exerts suppressive effects on tumor growth and cell pleomorphism by decreasing gene expression of VEGF, a key mediator of angiogenesis in cancer, and serum levels of the proinflammatory cytokines, IL-6 and IL-8 (Honarmand et al., 2019). CBD inhibition of VEGF and EGFR could help explain its protective effect against tumor invasiveness, migration and metastasis.  In recent years, the potential synergistic effects of CBD and chemotherapeutic drugs against (Honarmand et al., 2019) have also been evaluated. Enhancing the anticancer efficacy of CBD may help to reduce the required dose of these drugs in chemotherapy, which, in turn, may alleviate their adverse effects.

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On the other hand, artemisinin is a natural compound extracted from the plant Artemisia annua (sweet wormwood), known for its use in the treatment of malaria. In recent years, there has been growing interest in investigating its potential against cancer. Although artemisinin is not a conventional cancer treatment, studies suggest several mechanisms by which it may have anticancer effects. Within the mechanisms of action, we have:

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1. Generation of Free Radicals and Oxidative Stress: Artemisinin and its derivatives can generate oxygen free radicals in the presence of iron. These free radicals can induce oxidative stress in cancer cells, which can lead to apoptosis (programmed cell death) and inhibition of tumor growth. Oxidative Stress refers to an imbalance between the production of reactive oxygen species (ROS) and the body's ability to neutralize them with antioxidants. ROS, which include free radicals like superoxide and hydroxyl radicals, can damage cells, proteins, and DNA when they accumulate in excess. This imbalance can lead to cellular dysfunction and is associated with various diseases and aging processes.

2. Inhibition of Angiogenesis: Artemisinin can inhibit the formation of new blood vessels (angiogenesis) necessary for tumor growth and spread. This is due to its ability to affect growth factors and signals involved in the formation of blood vessels in tumors.

3. Modulation of Cell Signaling Pathways: Artemisinin can influence several cell signaling pathways related to cell growth and proliferation, such as the MAPK/ERK and PI3K/Akt pathways. By modifying these pathways, artemisinin can alter cancer cell proliferation and survival.

4. Induction of Apoptosis: Artemisinin can promote apoptosis in cancer cells by activating several proteins and enzymes involved in programmed cell death. This may include activation of caspases and upregulation of anti-apoptotic and pro-apoptotic proteins.

5. Cell Cycle Interference: Artemisinin may affect the cell cycle, preventing cancer cells from progressing through the cell cycle phases necessary for proliferation. This may contribute to the arrest of tumor growth.

 

Finally, genistein acts in the body through several key mechanisms, among them we can mention:

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Estrogen Receptor Modulation: Genistein is a phytoestrogen, which means that it can bind to estrogen receptors on cells. Depending on the context, it can act as an agonist (mimicking the effects of estrogen) or as an antagonist (blocking the effects of estrogen). This action is relevant in hormone-sensitive tissues, such as bone and the cardiovascular system.

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Antioxidant Properties: Genistein has antioxidant capacity, which means it can neutralize free radicals and reduce oxidative stress. This helps protect cells from oxidative damage, which is associated with aging and various chronic diseases.

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Aromatase Inhibition: Genistein can inhibit aromatase, an enzyme that converts androgens to estrogens. This action is particularly relevant in conditions related to elevated estrogen levels, such as certain hormone-dependent cancers.

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Modulation of Gene Expression: Genistein may affect the expression of genes related to important biological processes such as inflammation, cell growth and metabolism. This may influence a variety of health conditions, including cancers and metabolic diseases.

Anti-inflammatory Effects: Genistein may reduce inflammation by interfering with inflammatory pathways and decreasing the production of pro-inflammatory cytokines. This contributes to its potential to protect against inflammatory and chronic diseases

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​4. Important Information Before Using Vitacancer

 

Consult your doctor if:

• You are taking other medications, especially those metabolized by the liver (e.g., anticoagulants, anti-epileptics, antidepressants).

• You are pregnant or breastfeeding, as the safety of CBD during these periods is not fully established. Therefore, it is recommended to avoid use during these periods unless directed by a physician on a risk-benefit basis.

• You have pre-existing medical conditions, such as liver, kidney or cardiovascular disease.

 

Do not take Vitacancer if:

• You are allergic to cannabinoids, specifically CBD or any of the other components of this product.

• You are taking beta-blocker medications such as metoprolol, as it could potentiate the drug's mechanism of action inducing hypotension, dizziness and weakness.

 

 

5.  How to take Vitacancer oral solution​

Follow your doctor’s instructions and the product label for proper dosage. When taking cannabinoid-based drops sublingually, hold the liquid under your tongue for 60 to 90 seconds before swallowing. The effects typically begin within 20 to 30 minutes and last for approximately 6 hours.

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Taking the drops sublingually ensures that the cannabinoids bypass the digestive system, avoiding the breakdown of active compounds. This method increases bioavailability to 15%-35%, enhancing the product’s effectiveness while reducing potential drug interactions and ensuring a more stable therapeutic effect.

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Do not exceed the recommended dose.

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The recommended dose in adults is: 0,5 ml every 12 hours for a dose to 600 mg/daily.

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If you accidentally take more than the recommended dose, seek medical help immediately. Symptoms of overdose include: nausea, vomiting, seizures, heart problems (such as irregular heartbeat or cardiac arrest), lung conditions and altered mental status.

 

Recommendations:

• If you miss a dose, don't worry. Simply take the next dose at the regularly scheduled time the following day. Avoid double doses to make up for the missed dose.

• To help you remember, try to take Vitacancer at the same time each day.

• Do not discontinue Vitacancer without consulting your doctor, even if you begin to feel better. Consistent use is important to maintain its therapeutic effects.

• Make sure you always have enough Vitacancer on hand to avoid running out.

• If you have any questions or concerns about how to use this product, consult your doctor.

 

6. Possible side effects

If you experience a skin rash or any allergic reaction such as itching, swelling of the lips or tongue, wheezing or difficulty breathing, stop using the product immediately and seek medical advice as soon as possible.

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Common side effects (affecting more than 1 in 10 people) may include insomnia, headaches, diarrhea, nausea and fatigue.

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Rare side effects may include elevated liver enzymes (AST, ALT, GGT), seizures, status epilepticus, gait disturbances or abnormal behavior.

 

Adverse Event Reporting:

If you experience any type of adverse effect, consult your physician, even if it is a possible adverse effect not listed in this fact sheet. You can also communicate directly by email. By reporting adverse effects, you can help provide more information about the safety of this product.

 

7. Storage of Vitacancer oral solution

• Keep this product out of the sight and reach of children.

• Do not use this product after the expiration date indicated on the package. The expiration date is the last day of the month indicated.

• Store Vitacancer CBD oral solution at a temperature below 30 ºC.

 

8. Package contents and additional information

• Broad spectrum CBD oral solution.

• The active ingredient is Cannabidiol CBD. Each mL of solution contains: 600 mg Cannabidiol CBD (broad-spectrum CBD composed of a mixture of cannabinoids, including cannabigerol (CBG), cannabichromene (CBC), terpenes and flavonoids), 600 mg artemisinin, 40 mg genistein.

• The other ingredients are: Vitamin E, Vitamin C, Vitamin D, Coconut Oil, Sorbitan, Medium Chain Triglycerides.

• Product appearance and package contents:

• The oral solution is a viscous, amber colored liquid, oily consistency.

• The oral solution contains 30 mL.

 

 

9. Disclaimer

The information provided herein is based on extensive research conducted to develop Vitacancer and its proposed mechanisms of action. However, this information is intended for informational purposes only and does not constitute medical advice.

These statements and the product have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.